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Facts About CBD for Acne Relief

Can CBD help Relieve Acne?

Cannabidiol for Acne Relief

Can CBD help Acne?

One of the many problems all teenagers and adults go through together is dealing with skin problems, acne, and skin care related issues. Everyone knows it isn’t pleasant to look at, feel, or have. 

Evidence from a 2014 article in the Journal of Clinical Investigations suggests that CBD can halt the overproduction of oil secreted by the skin. This is one of the causes of acne, the most common human skin disease. Despite basic and applied research into the subject, an indisputable cure for acne does not yet exist. 

CBD does however hinder the creation of fats and oils in the skin, which are the cause of acne. CBDs have undergone multiple evaluations by the food and drug administration and other organizations for the effectiveness of CBD oil for acne and irritated skin

What is Acne?

Scientifically known as Acne Vulgaris, acne is caused by the inflammation of skin pores, excess oil production from the sebaceous glands in the skin, dead skin-cell buildup, and propionibacteria (a fat/lipid producing bacteria). 

The sebaceous glands are the glands in the skin that cause sebum production in your skin. When these things come together, acne is produced. This phenomena has plagued humanity for millennia.

Hyperproliferation of skin cells, or the abnormal excess creation of skin cells, is another cause for acne to be produced on the skin. The arguably most effective cure on the market for Acne Vulgaris is “Isotretinoin” (Brand name: Absorica, Zenatane, Myorisan) but Isotretinoin (FDA approved in 1982 for manufacturing by Hoffmann La Roche) is solely prescription based.

It also comes with a slew of unpleasant to downright horrible side effects, such as itching, changes in nail and skin texture, hair thinning and breakage on the head and face, dry mouth, nose, ears, throat, anus, high triglycerides, nausea, weight loss, and birth defects in pregnant women.

CBD offers a Natural alternative to such a horrible remedy, and why wouldn’t someone want an alternative when the FDA approved option is so bad?

How Does CBD Help Relieve Acne?

Today we have expensive facial scrubs, and fancy oil regulators, however, the non-psychotropic phytocannabinoid extracted from the cannabis plant known as CBD exhibits a trinity of anti-acne actions. CBD may well be one of the best treatments for acne and possibly other skin conditions like irritated skin.

The Journal of Clinical Investigation reports in its investigation for CBD as an acne treatment, that the endocannabinoid system (ECS) regulates multiple physiological processes. These include cutaneous cell growth and differentiation

CBD exerts universal antiinflammatory actions, decreases proliferation of sebocytes, and normalizespro-acne agents”.

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CBD Capsules

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What does this mean in plain English?

“Anti-inflammatory actions” are not steps you take to stop a bar fight. They are quite simply things that stop inflammation, like Tylenol or Advil. 

CBD has universal anti-inflammatory properties used in experimental models for treatment of Diabetes and Rheumatoid arthritis…and now acne. 

Sebocytes are the oil build-ups around hair follicles produced by the skin. If left to build up, they will cause acne. 

CBD exerts a sebostatic effect or a pausing of oil production in the skin. 

Lipogenesis is the process by which the body produces lipids (body fats).

CBD normalizes oil production in cases where the lipogenesis is occurring excessively. 

Such is the “cellular anti-acne trinity” of CBD.

Additional Benefits of CBD use to Relieve Acne

In addition to these effects, industrial hemp-derived CBD and Cannabis Sativa  have a reported antibacterial effect on skin, despite no research having been done into the effectiveness of CBDs on “acnegenic” Propionibacterium acnes strains. “Pro-acne agents” like oily skin are also countered by the effectiveness of CBD.

Keep in mind that there are additional factors that can lead to the formation and proliferation of blackheads. It is very important to note that, based on the literature, administration of CBD holds out the promise to target these factors as well. Indeed, CBD was shown to inhibit proliferation of hyperproliferative keratinocytes (A skin cell that produces keratin).  

CBD Products Recommended by Rx-420.com

Yes! You Can Cook With Hemp

Yes, You Can Cook With Hemp

Many consider hemp as the ultimate crop grown and harvested today. Its versatility makes it possible for hemp to be used in nearly countless ways and in so many different applications. Hemp is used to produce myriad commercial and industrial products, such as rope, textiles, clothing, shoes, food, paper, bioplastics, insulation, and biofuel. 

The most beneficial—and profitable—use for hemp is as a food source. Both hemp oil and seeds are an amazing superfood. They are high in Vitamin E, fiber, protein and contain Omega fatty acids—specifically, in a 3:1 ratio of Omega 3 to Omega 6. This ratio is widely acknowledged to be optimum for the human body.

If you’re not impressed by the list above, then also consider that hemp oil can also lower cholesterol, improve skin problems, and help with digestion. The following sections show you how you can effectively blend hemp into your diet.

A reminder: 

Don’t heat hempseed oil! The best way to use and consume 

the oil is either cold pressed or at room temperature.


Sprinkle hemp seeds on salads or fold them into a pesto or hummus for healthy texture and a bit of crunch.

Add hemp seed oil to any kind of salad dressing or mix. You can also mix it with citrus fruits and something sweet. Now you have a well-balanced dressing that will complement any combination of fruits. Other tasty add-ons are honey mustard, miso, and tart vinegars if you like. 


Make a smoothie even more healthy and beneficial simply by adding CBD and hemp oil. Hemp contains all 20 amino acids! That includes 9 amino acids that our bodies cannot produce. Hemp oil is great for a pre-workout smoothie, and tart berries (blackberries, cranberries, or strawberries) are a delightful and healthy addition.

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Every product we sell at Rx-420.com is derived from organic, non-GMO industrial hemp grown in Colorado, California, or Kentucky. All extractions are performed in GMP Certified facilities. Each product is batch numbered and each batch is sent to a third-party, independent, FDA Registered laboratory for testing. The results of the test are published with a COA that matches the batch number. The COA shows proof of the concentration of cannabinoids and proof that there has been no contamination.

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What is CBD? What is Cannabidiol?


Cannabidiol is a molecule that naturally occurs in the cannabis (a.k.a. hemp) plant. CBD and other substances extracted from the hemp plant have medicinal properties, but they do not cause the user to feel the short-term euphoric feeling of being “high” that is universally associated with smoking marijuana.

Many websites incorrectly state that CBD is not psychoactive (or psychotropic) when they actually mean that CBD does not make a person feel high. However, the molecule does “affect the brain,” which is the very definition of “psychoactive.”

For instance, CBD is known to increase the baseline dopamine levels in the brain, which helps treat depression. To be clear, CBD and other naturally occurring molecules in the cannabis must be defined as “psychoactive,” because they do, in fact, affect the brain; however, they do not make a person buzzed, chill, high, stoned, or any other euphemism used to describe an altered state. Therefore, the potential for abuse of CBD is near zero.

“Full-spectrum CBD” products include not only CBD, but also many, most, or all of the over 100 other chemical compounds that are produced by this plant. Collectively these compounds are known as cannabinoids. Of them, tetrahydrocannabinol (THC) is the most well known, being responsible for the high experienced by marijuana users.  Most interestingly, when full-spectrum complex’s are ingested, one molecule will act as a catalyst to a different molecule (occurring naturally in the hemp plant) to combine and create complex scaffoldings of of entirely new compounds.

The long-and-short of it is that CBD is one chemical compound naturally occurring in the cannabis plant. Full-spectrum CBD oils contain most or all of the other cannabinoids including some amount of THC unless otherwise indicated.

Merriam-Webster says:

a crystalline, nonintoxicating cannabinoid C21H30O2 found in cannabis and hemp that is sometimes used medicinally.

Charlotte’s Web: The Miracle of CBD in the Fight Against Childhood Epilepsy


The Beginnings of Cannabis Treatments for Children

Charlotte Figi was only 3 months old when she had her first seizure that lasted a nightmarishly-long 30 minutes. From that day forward, the seizures only got worse. Before long the baby suffered from multiple seizure episodes each day. Even worse, a single seizure could last up to four hours! By the time she was two, Charlotte had begun presenting Autistic behaviour patterns and showed indications of severe cognitive decline. At three years of age, Charlotte became non-verbal, could no longer eat, and was confined to a wheelchair. After seemingly endless doctor’s visits, young Charlotte was diagnosed with Dravet’s Syndrome, a rare and debilitating form of epilepsy.

No Success with Standard Treatments

Despite years of trial-and-error with some heavy-duty pharmaceuticals, by age five, Charlotte still suffered from up to 300 grand mal seizures a week. As one can imagine, this put a tremendous strain upon her already exhausted body. After an episode where her heart quit beating, doctors induced a coma just so that her poor body could recover from the trauma of these violent and prolonged seizures.

Charlotte’s doctors had no other options in their arsenal and their orthodox treatment regimen had not yielded many positive results, if any at all. Charlotte’s grandfather had related several stories he found in his research of some amazing results of parents using cannabis to treat their children suffering from epileptic seizures. Particularly notable was the success story of a young boy also diagnosed with Dravet’s. The family made the decision, after years of unsuccessful treatments to have Charlotte try cannabis extract.

At age 6, Charlotte’s parents finally succeeded in getting two doctors to prescribe a cannabis oil extract for Charlotte, not an easy feat to accomplish at the time because of her age. Prescription in hand, her father went to the medical dispensary and asked for the extract with the lowest THC and highest CBD. He mixed it into a form she could ingest and fed a small amount to his daughter. The results were drastic and almost immediate. Charlotte went from having seizures almost every two hours, 300 times a week to no seizures for an entire week.


At the time, the market for medical-grade cannabis low in THC was almost non-existent and the supplies of it reflected that. Charlotte had found her cure, but it wasn’t very profitable to produce since most medical users sought high THC extracts.

Stanley Brothers Accept the Challenge

The family approached the Stanley Brothers who are medical marijuana growers and dispensers from Colorado who agreed to cultivate a strain with the properties that Charlotte needed so desperately. They crossed a strain of low-THC medical marijuana with industrial hemp, jokingly calling it “Hippie’s Disappointment” because of its lack of THC, the molecule that causes users to feel “high”.


After the strain worked so well to stop this child’s seizures, the brothers changed the name to Charlotte’s Web in her honour.

An increasing number of scientific studies show CBD can regulate epileptic seizures without the side effects common with prescription pharmaceuticals.

How Does CBD Reduce Seizures?

The nervous system of the human body has an Endocannabinoid System (ECS), endocannabinoids are naturally produced cannabinoids that interact with cannabinoid receptors — CB1 and CB2. CB1 receptors are mainly found in the brain and are responsible for dealing with things like pain, movement coordination, cognitive abilities (thinking, memory), appetite and emotions. CB2 receptors are more commonly found in the immune system and have an effect on things like pain and inflammation.

When CBD is introduced to the human body, it interacts with the cannabinoid receptors and stimulates the body to produce more of its own endocannabinoids. Scientists are uncertain exactly how this reduces epileptic seizures.

Is CBD Right for You or Your Loved Ones?

Full-spectrum CBD extracts have low-toxicity and most side-effects are considered very mild. The potential for abuse is almost non-existent. CBDs have been used to successfully treat minors with the following medical conditions:

  • Epilepsy & Epileptic Seizures
  • Acne
  • Addiction Withdrawal Symptoms
  • Anti-inflammatory & Pain relief
  • Anxiety Disorders
  • Cancer
  • Diabetes (Type 1)
  • Obsessive Compulsive Disorder (OCD)
  • Post Traumatic Stress
  • Schizophrenia

UN Recommends Removal of CBD from Schedule IV under Convention of Narcotic Drugs

CBD and Hemp Oil CBD Products Recommended by Rx-420.com ARE Non-GMO Organic Laboratory Tested 100% US Made

The WHO Expert Committee on Drug Dependence (ECDD) recommended to the United Nations Secretary-General that pure CBD should not be scheduled at all within the UN International Drug Control Conventions. This recommendation comes almost a year after the committee agreed to review the matter. The committee further recommends that preparations containing predominantly cannabidiol and not more than .02% THC should not be under international control.

It is great news for those finding relief from the use of CBD products that the world’s leading health authority believes that CBD should not be a controlled product. This applies to the vast majority of the products that we have reviewed in our research. Many states have adopted a slightly higher threshold for legal THC content at .03%, but a vast array of products meet the stricter guideline set by the UN.

These recommendations reaffirm the safety and low likelihood of abuse of or addiction to cannabinoids

Can CBD Successfully Manage Pain?


Is it Safe to Treat Chronic Pain with CBD?

One of the largest and most successful group of CBD users are those who use CBD products for the treatment of chronic pain. CBD has been shown to reduce or eliminate pain, inflammation, and discomfort in those suffering from a variety of health conditions. In June, 2018 the FDA approved a CBD  oral solution sold under the trade name Epidiolex for the treatment of a rare form of epilepsy, but there are no other FDA approved uses. Additionally, only one product on the market today is tested at FDA certified labs for purity and concentrations. Always consult your primary care physician before beginning any treatment regimen.

CBD Oil is Not Approved by the FDA to Treat Many Types of Chronic Pain

CBD can be used to effectively treat chronic pain resulting from the following medical conditions:

  • Spine & Other Injuries
  • Arthritis
  • Cancer Treatment
  • Sickle-cell Anemia
  • Sciatica & Chronic Back Pain

Researcher are still unclear about the exact nature by which CBDs can reduce or eliminate pain, inflammation, and muscle spasms. We know that the human body produces neurotransmitters named endocannabinoids. Throughout the endocannabinoid system (ECS) are cannabinoid receptors. This system within the central nervous system is involved in a  physiological processes that include appetite, pain-sensation, mood, and memory. It is believed that CBD and other full-spectrum cannabinoids bind and interact with these receptors in a way that reduces or eliminates chronic pain.

Illustration of a synapse within the nervous system. Neurotransmitter receptors within the endocannabinoid system are located within the synapse.

What is the Best Way to Use CBD for the Treatment of Chronic Pain?

Once the CBD is extracted from the cannabis plant, the resulting “goo” is refined and processed to create many different products with many different applications. Although CBD can be found in an almost unimaginable number of concoctions, the following are the most common forms and usages of CBD and full-spectrum cannabinoids:

1. Tinctures (Oral Solutions)

Tinctures are made by adding a CBD extraction to either alcohol or glycol. The resulting liquid can then taken orally by swallowing the tincture immediately, allowing it to sit underneath the tongue for some time (sublingually), or sprayed into the mouth to coat it thoroughly before swallowing.

2. Capsules or Tablets

Capsules or tablets containing CBD are usually swallowed. However, there are proponents of starting at the other end of the digestive tract.

3. Lotions, Ointments, Balms, & Massage Oils

As is obvious to most, CBD in this form is for topical application. Those with experience using other essential oils recommend placing a hot, wet towel or cloth on the affected area immediately following application.

4. Edibles

CBD edibles take almost any form. The edibles themselves are made using CBD infused butters and oils. All candies, baked goods, and drinks are considered edibles including Gummy bears, fudge, caramels, lollipops, brownies, cookies, energy drinks; as well as the ingredient itself, infused oil or butter.

5. Vape Cartridge or Vape Juice

The most controversial way to administer CBD is through the use of electronic cigarettes, or Vape Pens. The jury seems to be out on whether or not vaping itself is harmful, or whether certain flavorings used in vape juices are harmful. There are reports of blistering of the lungs (cause unknown) and “popcorn lung” (caused by the flavoring
diacetyl) linked to vaping. For that reason, we do not recommend vaping CBD compounds.

If you insist, we recommend these best practices for vaping CBD to treat chronic pain:

  • Use only pure full-spectrum CBD that has been laboratory tested.
  • Use pure Propylene Glycol or pure Vegetable Glycerin.
  • Get Used to the Flavor and refrain from adding flavorings.
  • Use the lowest temperature possible that is still hot enough to vaporize the liquid. Some cannabinoids are destroyed at higher temperatures.
  • Use 3 parts vape juice to 2 parts CBD (500mg/fl oz)

CBD Dosage

Dosages vary by weight and by individual. Some people have a very low tolerance level to the effects of CBD and others have higher tolerance levels. The staff at this website are not trained medical professionals and the opinions expressed are our interpretations of the research available and our own experience. As with any new treatment, use caution and do more research. I am confident that you cannot overdose or become dependent on CBD, please do not be the Darwin Award winner that proves me wrong. If you are taking other medications, ask your doctor or pharmacist if CBDs are contraindicated.

Allergy Warning

The very rare individual may be allergic to THC, CBD, or another cannabinoid. If you have never been exposed to cannabis, or if you have had a negative reaction in the past, it is prudent to test for hemp allergies by rubbing a small amount of the product you intend to use on the inside of your arm. If no redness, swelling, or other indicator of an allergic reaction occurs after one hour, the product should be safe for topical use. If the product is to be ingested, rub a small amount of the oil on your lips. Indicators of an allergic reaction include stinging or swelling. If you show no signs of a negative reaction, swish a small amount in your mouth and spit out the remainder. If after 30-60 minutes everything feels normal, you are probably not allergic to Cannabinoids.

CBD Dosage Calculator for Treatment of Chronic Pain

Using CBD for pain requires building up to a level that saturates the body with the molecule. This process usually takes 2-3 days of regular doses to bring CBD levels to the level required to reduce or entirely eliminate chronic pain. Do not be discouraged when you have no relief from your chronic pain after 1 dose (or even several doses). It will take a couple of days.

Typical effective dosages are between 5 – 50mg of CBD per day. That’s an order of magnitude difference! It’s ok, you can find your right dosage. It won’t take long to find the dosage that is right for you. First off, you or your loved one is in pain. You cannot overdose, or get stoned on CBD no matter how much you take, so start at your max dose immediately. If you are under 200 lbs (90 kg) take 25mg of CBD each day for the first two days. Increase dosages in proportion to body mass up to 50mg for someone weighing 400 lbs. No matter the amount of CBD required, we find the best results come from splitting the daily amount into several smaller doses to be taken throughout the day.

Inventory the Effects of CBD for Chronic Pain on Days 3 & 4

Once you’ve taken 25-50 mg of CBD for 2 or 3 full days, you should have relief from the chronic pain. We pray that you find great relief. If you do, fantastic! You have found a miracle drug. You could keep ingesting the same quantity and there are no indications it would ever hurt you. For the sake of conservation, begin lowering your daily dosage until the pain hints that it will return. For instance if you found relief taking 25 mg of CBD a day after 2 days, consume 20 mg on days 3-5. If there is still no pain, take 15 mg on days 6-10. If the pain is still being relieved, lower the dosage to 10 mg per day for the next week. If that is still taking care of the pain, try 5 mg of CBD per day. It’s unlikely you can get that low unless you weigh under 100 lbs, but possible even if you weigh more. If at any time you feel the pain creep back in, raise the dosage back up to the last daily dosage that was effective.

Possible Side-effects of Using CBD

Negative side-effects can possibly include sleepiness, sedation and lethargy; elevated liver enzymes; decreased appetite; diarrhea; rash; fatigue, malaise and weakness; insomnia, sleep disorder and poor quality sleep; and infections. Discontinue use immediately and consult your physician if you experience any of these side effects.

Positive side-effects may include boosted energy, increased immune response, weight-loss, pain relief, increased cognitive ability, and a clear complexion. If you experience any of these side-effects, let the good times roll.

The Bright Side of Using CBD Extracts to Treat Chronic Pain

While you must build up the concentration of CBD in your body to get relief from chronic pain, you get those days back on the backend. Should you stop taking CBD, it will take a couple of days for the pain to return to untreated levels.

It is perfectly fine to stop taking CBD “cold-turkey”.

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